RARECHEM AH BS 0105
1H-indol-3-ol
CAS: 480-93-3
Molecular Formula: C8H7NO
RARECHEM AH BS 0105 - Names and Identifiers
| Name | 1H-indol-3-ol |
| Synonyms | ISI-6-0026 1H-indol-3-ol 3-HYDROXYINDOLE 3-Hydroxyindole 1-Boc-1H-Indol-3-ol RARECHEM AH BS 0105 3-Hydroxy-1H-indole 1,2-DIHYDRO-INDOL-3-ONE 1,2-Dimethylindole-3-carboxaldehyde |
| CAS | 480-93-3 |
| InChI | InChI=1/C8H7NO/c10-8-5-9-7-4-2-1-3-6(7)8/h1-5,9-10H |
RARECHEM AH BS 0105 - Physico-chemical Properties
| Molecular Formula | C8H7NO |
| Molar Mass | 133.15 |
| Density | 1.1475 (rough estimate) |
| Melting Point | 85-87 °C |
| Boling Point | 245.66°C (rough estimate) |
| Solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| Appearance | Solid |
| Color | Dark Green to Black |
| pKa | 10.10±0.40(Predicted) |
| Storage Condition | Amber Vial, -20°C Freezer, Under inert atmosphere |
| Stability | Light Sensitive |
| Refractive Index | 1.5260 (estimate) |
RARECHEM AH BS 0105 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| Hazard Note | Irritant |
RARECHEM AH BS 0105 - Introduction
1H-indol-3-ol is an organic compound with the chemical formula C8H7NO, commonly abbreviated as I3O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 1H-indol-3-ol is a white or light yellow solid.
-Solubility: It is slightly soluble in water, but more soluble in organic solvents such as ethanol and dichloromethane.
-Melting point: Its melting point is about 122-126 degrees Celsius.
-Structure: It is a derivative of indole, with a structure in which a hydroxyl group is connected to an indole ring.
Use:
-Biochemistry: 1H-indol-3-ol is an important biologically active molecule that can be used as a substrate for enzyme reactions, a raw material for natural hormones and a precursor for fluorescent dyes.
-Drug research: It is used as an intermediate for synthetic drugs in drug research. It has anti-tumor, anti-inflammatory and antibacterial activities, and may have potential medicinal value.
-Research: 1H-indol-3-ol is widely used in chemical and biological research, such as the synthesis of organic compounds, dyes and liquid crystals.
Preparation Method:
The conventional synthesis method of-1H-indol-3-ol is obtained by the oxidation reaction of indole. One common synthetic method is the oxidation of indole using an oxidizing agent, such as hydrogen peroxide or ammonium persulfate.
-In the preparation process, indole first reacts with an oxidizing agent to generate indole -3-monooxide, and then 1H-indol-3-ol is obtained by hydrolysis.
Safety Information:
- 1H-indol-3-ol generally has low toxicity under normal use conditions, but it is still necessary to pay attention to correct use and storage.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help and advice.
-when carrying out experimental operation, should wear appropriate protective equipment, such as gloves, protective glasses and experimental clothes.
-When using or handling 1H-indol-3-ol, the relevant safety operating regulations and laboratory regulations should be observed.
Nature:
-Appearance: 1H-indol-3-ol is a white or light yellow solid.
-Solubility: It is slightly soluble in water, but more soluble in organic solvents such as ethanol and dichloromethane.
-Melting point: Its melting point is about 122-126 degrees Celsius.
-Structure: It is a derivative of indole, with a structure in which a hydroxyl group is connected to an indole ring.
Use:
-Biochemistry: 1H-indol-3-ol is an important biologically active molecule that can be used as a substrate for enzyme reactions, a raw material for natural hormones and a precursor for fluorescent dyes.
-Drug research: It is used as an intermediate for synthetic drugs in drug research. It has anti-tumor, anti-inflammatory and antibacterial activities, and may have potential medicinal value.
-Research: 1H-indol-3-ol is widely used in chemical and biological research, such as the synthesis of organic compounds, dyes and liquid crystals.
Preparation Method:
The conventional synthesis method of-1H-indol-3-ol is obtained by the oxidation reaction of indole. One common synthetic method is the oxidation of indole using an oxidizing agent, such as hydrogen peroxide or ammonium persulfate.
-In the preparation process, indole first reacts with an oxidizing agent to generate indole -3-monooxide, and then 1H-indol-3-ol is obtained by hydrolysis.
Safety Information:
- 1H-indol-3-ol generally has low toxicity under normal use conditions, but it is still necessary to pay attention to correct use and storage.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help and advice.
-when carrying out experimental operation, should wear appropriate protective equipment, such as gloves, protective glasses and experimental clothes.
-When using or handling 1H-indol-3-ol, the relevant safety operating regulations and laboratory regulations should be observed.
Last Update：2024-04-09 15:17:58
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Spot supply
Product Name: Phenylephrine Impurity 54 Visit Supplier Webpage Request for quotationCAS: 480-93-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple Specifications
Product Name: 3-Hydroxyindole Visit Supplier Webpage Request for quotationCAS: 480-93-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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